Closeup of Midwestern states on black and white illustrated broken US map

Great Private Comprehensive Undergraduate Colleges in the Midwest

Looking for a comprehensive college that offers everything from bachelor’s degrees to doctoral programs? Check out these great options in the Midwestern US.

Are you searching for a school that offers both liberal arts and professional studies? How about a big, vibrant campus where you can also receive one-on-one attention from faculty? If this sounds like your college search criteria, then you’re in the right place. This list features private comprehensive colleges and universities in the Midwest that offer a wide range of degree programs from baccalaureate to doctoral, cutting-edge teaching and research facilities, and other exciting opportunities for students. Learn more about them and request information in just one click with the green “Connect me” buttons underneath each school. Your comprehensive college search just got easier!

Creighton University

Creighton University logoCreighton University is a private comprehensive institution on the edge of downtown Omaha, Nebraska. The University offers more than 60 majors in the Arts & Sciences, Business, and Nursing, plus 45+ graduate and professional programs. Over 4,000 undergraduates benefit from an 11:1 student-faculty ratio, an average class size of 22, and an abundance of research opportunities, with 36% of undergrads participating in research that results in hundreds of national and international presentations each year. 

Connect me with Creighton!

Drake University

Drake University logoDrake University is a private comprehensive university in Des Moines, Iowa. The University is home to nearly 3,000 undergraduate students who study in more than 150 majors, minors, and concentrations through seven schools and colleges. Drake’s expert faculty members acknowledge that experience is the best teacher, offering students in every major abundant opportunities to learn by doing through internships, professional and career development services, and student leadership opportunities.

Connect me with Drake!

Indiana Wesleyan University

Indiana Wesleyan University logoIndiana Wesleyan University is a private comprehensive Christian liberal arts university in Marion, Indiana—65 miles from Indianapolis. Nearly 3,000 undergraduates pursue over 80 degrees in Business, Technology, Education, Science, Ministry, Nursing, and more. IWU also offers cutting-edge facilities and residence halls, a diverse range of student organizations, and a 97% career outcomes rate.

Connect me with IWU!

Lawrence Technological University

Lawrence Technological University logoLawrence Technological University is a private comprehensive university in Southfield, Michigan—just 20 miles from the center of Detroit. LTU offers around 100 programs through the Colleges of Architecture & Design, Arts & Sciences, Business & Information Technology, and Engineering. Approximately 3,000 students from 37 states and 50 countries benefit from an 11:1 student-faculty ratio and receive a high-end laptop loaded with industry-standard software, retailing at over $75,000 on average.

Connect me with LTU!

Lewis University

Lewis University logoLewis University is a private comprehensive Catholic university in Romeoville, Illinois. Lewis is a dynamic university offering more than 80 undergraduate majors, 37 graduate programs, and two doctoral programs to 6,500 undergraduate and graduate students. With more than 100 clubs and organizations and 23 intercollegiate NCAA Division II athletic teams, campus activities include theatre and performing arts, intramural and club sports, a nationally recognized scholars program, peer ministry, and volunteerism.

Connect me with Lewis!

Ohio Northern University

Ohio Northern University logoOhio Northern University is a private comprehensive Methodist institution in the small rural village of Ada, Ohio—90 minutes from Columbus. More than 3,000 students from all 50 states and 15 countries are enrolled in a variety of majors, minors, professional programs, and concentrations through the Colleges of Arts & Sciences, Business Administration, Engineering, and Pharmacy. ONU also offers an average class size of 19, a student-faculty ratio of 12:1, 200+ clubs and organizations, and 23 athletic teams competing in NCAA Division III.

Connect me with ONU!

St. Catherine University

St. Catherine University logoSt. Catherine University is a comprehensive liberal arts institution located in central St. Paul, Minnesota. At the heart of the University is the College for Women, a traditional undergraduate program with nearly 4,000 students and over 60 majors, plus 35 more programs in partnership with neighboring colleges and universities. St. Kate’s also offers a strong orientation program, peer mentors, 70+ chartered clubs and organizations, and 28 National Honor Society chapters.

Connect me with St. Kate’s!

Trine University

Trine University logoTrine University is an independent nondenominational comprehensive university in Angola, Indiana—40 miles from Fort Wayne. Over 5,000 students benefit from a 17:1 student-faculty ratio, an average class size of 19.8, and more than 40 career-focused undergraduate majors in the Arts & Sciences, Business, Education, Health Sciences, and Engineering. The University also has more than 60 clubs and organizations, 36 competitive athletic teams, and a championship golf course that’s hosted PGA events and NCAA national championships.

Connect me with Trine!

University of Chicago

University of Chicago logoThe University of Chicago is a private comprehensive university located seven miles south of downtown Chicago, Illinois. Approximately 6,800 undergraduates pursue over 50 majors and more than 40 minors, with the opportunity to double-major, create their own, or explore interdisciplinary opportunities. UChicago also features a rigorous liberal arts curriculum, small discussion-style seminars, a 5:1 student-faculty ratio, more than 3,000 offered courses, nearly 60 faculty-designed and taught study abroad programs, and 400+ student organizations.

Connect me with UChicago!

University of Detroit Mercy

University of Detroit Mercy logoThe University of Detroit Mercy is a private coeducational Roman Catholic institution with three campuses in Detroit, Michigan. With nearly 5,000 students and an 11:1 student-faculty ratio, the University offers more than 100 academic programs as well as 70+ on-campus student clubs and organizations. Other benefits of attending Detroit Mercy include intricate study abroad programs, community service projects, research opportunities with award-winning faculty,  competitive internships at major organizations in Detroit and beyond, and more.

Connect me with Detroit Mercy!

Looking for more great options for undergrads? Explore all our featured undergraduate school profiles to learn more and get recruited quickly and easily!

Like what you’re reading?

Join the CollegeXpress community! Create a free account and we’ll notify you about new articles, scholarship deadlines, and more.

Join Now

Join our community of
over 5 million students!

CollegeXpress has everything you need to simplify your college search, get connected to schools, and find your perfect fit.

Join CollegeXpress
Cameron Lee

Cameron Lee

High School Class of 2022

I used CollegeXpress to search for colleges. It helped me narrow down the schools on the West Coast and which schools had Construction Engineering programs. I made my decision to go to OSU and I am so excited about it.

Sonny Harris

Sonny Harris

College Student

For the entire year before college, I spent a lot of time deeply considering what major I wanted to go into and how to fund my higher education. After a lot of research, I came across CollegeXpress, which helped me ultimately find a ton of scholarships for which I could apply—and some of which I received! If it weren’t for CollegeXpress, I may not have found those scholarships as they didn't appear on any other scholarship search forum. Additionally, I learned more about the options I had been considering for my major through CollegeXpress’s resources. In the end, I chose to major in Computer Science, as it seemed best suited to me and the careers in the field seemed enjoyable, and I've never been more excited to move into my future! Ultimately, I want to thank CollegeXpress for offering their services. I received enough financial aid in scholarships to fund my entire freshman year of college and even got some money refunded which I used to purchase a new laptop, and I bought all of the books I needed for the semester!



High School Class of 2021

CollegeXpress gave me options of schools with my major and from there I was able to pick what was most important to me in a school. Everything was so organized that I could see all the information I needed.

Alexandra Adriano

Alexandra Adriano

$2,000 Community Service Scholarship Winner, 2016

I've used CollegeXpress quite a bit as a senior, particularly for colleges and scholarships, so it's been a very big asset in that respect! I would recommend it to anyone looking to pursue a college education, especially seniors! This scholarship will help me achieve my goals in ways I couldn't have before, and I know that there are opportunities like that for everyone on the website and in the magazines!

Joseph Johnsly

Joseph Johnsly

High School Class of 2021

It's an honor for me to be writing to share a little about my experience with CollegeXpress. I've been using CollegeXpress for about a year now, and the reason why I chose it is because it provides astonishing scholarships for every student around the globe. Besides that, this organization dispenses all the information necessary to help students get to college. CollegeXpress has helped me have an easier experience with applying to colleges and choosing the best fit for myself.

College Matches

Colleges You May Be Interested In

Drew University

Madison, NJ

Goldey-Beacom College

Wilmington, DE

Marymount University

Arlington, VA

Fort Lewis College

Durango, CO